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Eur Respir J 1991; 4: 905-911
Copyright © ERS Journals Ltd 1991

Case Studies

Bronchiolitis obliterans organizing pneumonia and rheumatoid arthritis

RJ van Thiel, S van der Burg, AD Groote, GD Nossent, and SH Wills

Bronchiolitis obliterans, with or without organizing pneumonia, can be a serious and life-threatening complication of rheumatoid arthritis. We describe a case of bronchiolitis obliterans organizing pneumonia in a patient who recently developed rheumatoid arthritis, presenting as a severe respiratory insufficiency. Diagnosis was made by means of open lung biopsy. Treatment with corticosteroids induced a quick response and substantial improvement of the respiratory symptoms. A simultaneous strong rise in titres of serological tests suggests a relationship between the bronchiolitis obliterans organizing pneumonia and the rheumatoid arthritis.


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