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Lung transplant outcomes: a review of survival, graft function, physiology, health-related quality of life and cost-effectiveness

¹ The University of Pittsburgh Medical Center, Division of Pulmonary, Allergy and Critical Care Medicine, Pittsburgh, PA, ⁴ Johns Hopkins Hospital, Baltimore, MD, USA, ² St. Paul's Hospital and ³ British Colombia Transplant Society, Vancouver, BC, Canada.

CORRESPONDENCE: J.B. Orens, Johns Hopkins Hospital, 1830 E Monument St, 5th floor, Baltimore, MD 21205, USA. Fax: 1 4109550036, E-mail: Jorens@jhmi.edu

Keywords: Cost, function, lung transplantation, outcomes, quality of life, survival

Received: June 3, 2004
Accepted June 6, 2004

Abstract

The success of lung transplantation has improved over time as evidenced by better long-term survival and functional outcomes. Despite the success of this procedure, there are numerous problems and complications that may develop over the life of a lung transplant recipient. With proper monitoring and treatment, the frequency and severity of these problems can be decreased. However, significant improvement for the overall outcomes of lung transplantation will only occur when better methods exist to prevent or effectively treat chronic rejection.

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