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Eur Respir J 1999; 14: 475-477
Copyright © ERS Journals Ltd 1999

Case Studies

Left bronchial isomerism, normal atrial arrangement and bronchomalacia mimicking asthma: a new syndrome?

A Bush

Three children who presented with steroid-resistant airflow obstruction are described. They all had bronchomalacia in the setting of a rare visceral arrangement, namely left bronchial isomerism with normal atrial arrangement. Imaging and, in two cases, a normal residual volume in the face of severe airflow obstruction were diagnostic pointers to a nonasthmatic cause of wheeze. Although the association of these abnormalities may be coincidental, together they may constitute a new clinical syndrome.


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A. B. Chang and W. B. Glomb
Guidelines for Evaluating Chronic Cough in Pediatrics: ACCP Evidence-Based Clinical Practice Guidelines
Chest, January 1, 2006; 129(1_suppl): 260S - 283S.
[Abstract] [Full Text] [PDF]


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